June 20th and 21st 2019

Neurosciences in Intensive Care International Symposium 2019 (NICIS)

Place : Institut Pasteur PARIS
Theme : Neuroscience of prognostication in the ICU

The vision of Neurosciences in Intensive Care International Symposium (NICIS) is to accelerate transformative advances in the care and science of patients with critical illness and neurological injury. Participants are clinicians and scientists who have a common aspiration to translate discoveries in the neurosciences into better patient-centered outcomes.Since 2017, two NICIS events are offered, one in Washington (NICIS.America) and the other in Paris (NICIS.Europe), held respectively in March and June.

The 2019 edition of NICIS-Europe is titled Neuroscience of prognostication in the IC. It will be held on June the 20th-21st 2019 at the Institut Pasteur in Paris.

NICIS-Europe 2019 builds on the success of previous editions, which were devoted to “The Neurosciences of critical illness and acute CNS infection” (2018); « Critical illness: Ageing, frailty and resilience » (2017), « Neuro-inflammation in Critical illness: From brain signalling to brain insult » (2016), « Neuroscience of repair, regeneration and recovery from critical illness » (2015), and « Neurobiology of stress  » (2014).

Prognostication of the neurological outcome of primary brain injured patients is a major challenge for the intensivist, raising both medical and ethical issues. Advances in Neurosciences allow us to better predict the recovery of arousal or consciousness in post-anoxic or traumatic brain injury patients. Despite these advances, prediction models continue to have limited accuracy, possibly contributing to flawed medical decision-making and suffering of families and caregivers. Moreover, medical decision-making may be influenced a range of societal and cognitive biases. Finally, prediction need to integrate therapeutic interventions to gain in discriminative value.

But the challenge and opportunity of neuroprognostication is not limited to post-anoxic or traumatic brain injury patients. It concerns a much broader population of critically ill patients. Indeed, with the aging population, an increasing proportion of patients admitted to the Intensive Care Unit have pre-existing neurodegenerative diseases. In addition, more than a third of patients discharged from ICU will develop a new or worsening impairment of functional and cognitive status. There is an unmet need for higher performing prediction systems to determine long-term post-ICU outcome and propose adapted preventive or curative strategies. Better prediction will need to be driven by translating knowledge gained on the biological mechanisms of brain injury and repair. This translational approach is at the core of NICIS 2019.

NICIS-Europe 2019 speakers include thought leaders in cellular and molecular biology, biomarker discovery and validation, neurophysiology, neuroimaging and brain mapping, and advanced clinical trial design. The conference is designed for an interdisciplinary audience of clinicians and investigators working in neuroscience and critical care medicine. This will be a unique opportunity to have an interactive and lively discussion between multiple content-experts with contrasting perspectives.

All conference participants are invited to submit abstracts of original data for consideration at our Poster Presentation Session.

We would like to acknowledge support from the Société Française d’Anesthésie-Réanimation (SFAR), the Association des Neuro-Anesthésistes de langue Française (ANARLF), the International Society of International Symposium of Intensive Care and Emergency Medicine (ISICEM), the Société de Réanimation de Langue Française (SRLF) and the Institut Pasteur for their support or endorsement. Our special thanks go to the University of Versailles, the Paris-Descartes University, The Pierre Marie Curie University, Columbia University and Johns Hopkins University.

We look forward to welcoming you in June for NICIS-EUROPE 2019 !

Yours sincerely,

Tarek Sharshar
Fernando Bozza
Jan Claassen
Vincent Degos
Romain Sonneville
Robert D Stevens

AND THE JUNIOR MEMBERS

NICIS America

NICIS America :

EDA annual meeting

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